Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407707 | 0.88 | EGLN1 (0.54) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523235 | 0.86 | EGLN1 (0.70) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL4411746 | 0.85 | EGLN1 (0.61) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL4757084 | 0.84 | EGLN1 (0.61) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL4757876 | 0.83 | EGLN1 (0.59) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL4409796 | 0.82 | EGLN1 (0.64) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL4411721 | 0.82 | EGLN1 (0.58) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL5318629 | 0.81 | EGLN1 (0.66) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL5027666 | 0.80 | EGLN1 (0.68) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1841936 | 0.80 | EGLN1 (0.56) | EGLN1FTOBBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146425-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF CHEMOTHERAPY-INDUCED ANEMIA | FIBROGEN, INC. (US) | 2007-12-21 | — | — | WO | disclosed |