Biphenyl

Biphenyl

SCHEMBL4757940

CC(C)OC(=O)NCC1CCC(C(=O)O)CC1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
VCP P55072 11/20 0.48
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8226327 0.89 KMT2A (0.56) KMT2AMEN1
SCHEMBL4654602 0.89 KMT2A (0.45) VCPKMT2AMEN1
SCHEMBL4654689 0.82 KMT2A (0.48) KMT2AMEN1
SCHEMBL914468 0.81 KMT2A (0.45) VCPHDAC3HDAC4HDAC1HDAC7
SCHEMBL914469 0.81 KMT2A (0.45) VCPHDAC3HDAC4HDAC1HDAC7
SCHEMBL8291594 0.80 TDP1 (0.47) KMT2AMEN1
SCHEMBL915910 0.80 KMT2A (0.43) VCPHDAC3HDAC4HDAC1HDAC7
SCHEMBL915909 0.80 KMT2A (0.43) VCPHDAC3HDAC4HDAC1HDAC7
SCHEMBL915159 0.78 VCP (0.43) VCPKMT2AMEN1
SCHEMBL915160 0.78 VCP (0.43) VCPKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC VCP 4813/4885HDAC3 727/4885HDAC4 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.