SCHEMBL4757961

SCHEMBL4757961

OP(O)(=S)SNc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.40
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 4/20 0.39
TSHR P16473 4/20 0.39
TAS2R38 P59533 3/20 0.39
TP53 P04637 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
EPHX1 P07099 1/20 0.39
EPHX2 P34913 1/20 0.39
CDK9 P50750 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
CYP3A4 P08684 1/20 0.39
IDO1 P14902 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
GAA P10253 4/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29052006 0.77 CA9 (0.47) HSD17B10TSHRTP53SMN1; SMN2EPHX1
SCHEMBL11614917 0.72 ALDH1A1 (0.37) PHGDHALDH1A1HSD17B10TSHRTAS2R38
Diphenylamine SCHEMBL29103683 0.70 HSD17B10 (0.67) ALDH1A1HSD17B10TSHRTAS2R38SMN1; SMN2
Diphenylamine SCHEMBL28401404 0.70 HSD17B10 (0.67) ALDH1A1HSD17B10TSHRTAS2R38SMN1; SMN2
Diphenylamine SCHEMBL29103681 0.70 HSD17B10 (0.67) ALDH1A1HSD17B10TSHRTAS2R38SMN1; SMN2
SCHEMBL6831562 0.69 ALDH1A1 (0.44) PHGDHALDH1A1HSD17B10TSHRTAS2R38
SCHEMBL3226501 0.67
SCHEMBL2552416 0.66 ALDH1A1 (0.50) PHGDHALDH1A1HSD17B10TSHRTAS2R38
SCHEMBL4557133 0.66 ALDH1A1 (0.50) PHGDHALDH1A1HSD17B10TSHRTAS2R38
SCHEMBL2552419 0.65 ALDH1A1 (0.43) PHGDHALDH1A1HSD17B10TSHRTAS2R38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008019451-A1 COLLECTORS AND FLOTATION METHODS AB TALL (HOLDINGS) PTY LTD (AU) 2008-02-21 WO claimed
CN-117772405-B Beneficiation method for difficultly-separated mixed lead-zinc ore 矿冶科技集团有限公司 2024-05-31 CN disclosed
CN-117772405-A Beneficiation method for difficultly-separated mixed lead-zinc ore 矿冶科技集团有限公司 2024-03-29 CN disclosed
US-20150209801-A1 MONOTHIOPHOSPHATE CONTAINING COLLECTORS AND METHODS TEEBEE HOLDINGS PTY LTD (AU) 2015-07-30 US disclosed
WO-2014012139-A1 MONOTHIOPHOSPHATE CONTAINING COLLECTORS AND METHODS TEEBEE HOLDINGS PTY LTD (AU) 2014-01-23 WO disclosed
WO-2008019451-A1 COLLECTORS AND FLOTATION METHODS AB TALL (HOLDINGS) PTY LTD (AU) 2008-02-21 WO disclosed