Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757961 | 0.77 | PHGDH (0.40) | CA9CA12TP53EPHX1TSHR | |
| Diphenylamine SCHEMBL27245440 | 0.70 | HSD17B10 (0.67) | CA9CA12TSHRCA2CA4 | |
| Diphenylamine SCHEMBL28255754 | 0.70 | HSD17B10 (0.67) | CA9CA12TSHRCA2CA4 | |
| Diphenylamine SCHEMBL27245439 | 0.70 | HSD17B10 (0.67) | CA9CA12TSHRCA2CA4 | |
| SCHEMBL3071192 | 0.70 | CA9 (0.44) | CA9CA12TP53EPHX1TSHR | |
| SCHEMBL28307958 | 0.70 | ALOX15 (0.50) | CA9CA12SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8081387 | 0.69 | CA9 (0.52) | CA9CA12TP53EPHX1TSHR | |
| SCHEMBL195068 | 0.69 | CA9 (0.52) | CA9CA12TP53EPHX1TSHR | |
| Phosphoric Acid SCHEMBL28208351 | 0.69 | IDO1 (0.74) | CA9CA12TP53EPHX1TSHR | |
| Phosphoric Acid SCHEMBL27855618 | 0.69 | IDO1 (0.74) | CA9CA12TP53EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118284692-A | Gene editing of PCSK9 or ANGPTL3 and compositions and methods of using same for treating diseases | 维乎医疗有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117580950-A | Compositions and methods for treating TDP-43 proteinopathies | 梅兹治疗公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117042797-A | Compositions and methods for treating hepatitis b virus infection | 维尔生物科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116917338-A | Methods and compositions comprising PD1 chimeric polypeptides | 西雅图儿童医院（DBA西雅图儿童研究所） | 2023-10-20 | — | — | CN | disclosed |
| CN-116390943-A | Engineered hepatitis b virus neutralizing antibodies and uses thereof | 维尔生物科技有限公司 | 2023-07-04 | — | — | CN | disclosed |