Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755473 | 0.79 | GRIN2B (0.40) | GAA | |
| SCHEMBL4757548 | 0.75 | CHRM3 (0.46) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4755434 | 0.70 | CHRM3 (0.41) | CHRM3CHRM2CHRM1KCNH2 | |
| SCHEMBL431187 | 0.70 | HTT (0.59) | CHRM3HTTCHRM2LMNACYP2D6 | |
| SCHEMBL4560569 | 0.69 | HTT (0.51) | HTTMAPTKMT2A | |
| SCHEMBL3226891 | 0.69 | CHRM3 (0.47) | CHRM3CHRM2LMNACYP2D6CHRM1 | |
| SCHEMBL27927747 | 0.69 | HTT (0.54) | CHRM3HTTCHRM2LMNACYP2D6 | |
| SCHEMBL12918262 | 0.68 | ACHE (0.41) | CHRM3CHRM2CHRM1KCNH2RAB9A | |
| SCHEMBL3214855 | 0.68 | KEAP1 (0.46) | CHRM3CHRM2CYP2D6CHRM1HRH1 | |
| SCHEMBL3224624 | 0.68 | POLB (0.52) | CHRM3HTTCHRM2CYP2D6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |