SCHEMBL4758055

SCHEMBL4758055

C=C(C(=O)O)C(O)C=CO

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TET2 Q6N021 3/20 0.30
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728394 0.78 TDP1 (0.32) TDP1
SCHEMBL11700571 0.75 TET2 (0.31) MEN1MAPTRECQLKMT2ATDP1
SCHEMBL38691 0.74
SCHEMBL16703910 0.74
Methacrylic Acid SCHEMBL6877602 0.67 TP53 (0.32) TDP1
SCHEMBL1230378 0.66
SCHEMBL1326397 0.65 LMNA (0.35) MEN1KMT2ATET2TET3TET1
SCHEMBL9278644 0.65
SCHEMBL2458002 0.63 TP53 (0.38) MAPTTET2TET3TET1
SCHEMBL419091 0.63 TP53 (0.38) MAPTTET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1253134-B1 Vinyl-polymerizable monomer having tertiary hydroxyl group and polymer MITSUBISHI GAS CHEMICAL CO (JP) 2008-11-26 EP disclosed