SCHEMBL1326397

SCHEMBL1326397

C=CC(C=C)C(=C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
TET2 Q6N021 3/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16703910 0.80
SCHEMBL38691 0.80
SCHEMBL23581465 0.74 TSHR (0.38) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL1135900 0.72 LMNA (0.32) LMNATET2TET3TET1ALOX15
SCHEMBL1948588 0.72
SCHEMBL17137797 0.72
SCHEMBL11879827 0.72
SCHEMBL5872870 0.72
SCHEMBL471880 0.72
SCHEMBL18277280 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823592-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT The Hong Kong University Of Science And Technology (CN) 2021-05-26 EP claimed
CN-112702992-A Compositions and methods for controlled release of target agents 香港科技大学 2021-04-23 CN claimed
WO-2020015737-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2020-01-23 WO claimed
JP-4721702-B2 2011-07-13 JP claimed
EP-1515784-A1 SEPARATION SYSTEM, COMPONENTS OF A SEPARATION SYSTEM AND METHODS OF MAKING AND USING THEM Teledyne Isco, Inc. (US) 2005-03-23 EP claimed
WO-2004002603-A1 SEPARATION SYSTEM, COMPONENTS OF A SEPARATION SYSTEM AND METHODS OF MAKING AND USING THEM ISCO, INC. (US) 2004-01-08 WO claimed
US-20230093832-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2023-03-30 US disclosed
US-11571283-B2 Bonding of soft gingival tissues with dental prostheses ESTHETIC IMPLANT SOLUTIONS, LLC (US) 2023-02-07 US disclosed
US-20230012924-A1 COMBINATION OF CROSSLINKERS TO IMPROVE COATING PROPERTIES BASF SE (DE) 2023-01-19 US disclosed
CN-115135303-A Compositions and methods for controlled release of target agents 香港科技大学 2022-09-30 CN disclosed
WO-2021143736-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2021-07-22 WO disclosed
US-20210220266-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) 2021-07-22 US disclosed
WO-2021126780-A1 COMBINATION OF CROSSLINKERS TO IMPROVE COATING PROPERTIES BASF SE (DE) 2021-06-24 WO disclosed
US-7498394-B2 (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2009-03-03 US disclosed
CN-100392182-C Printing coated paper JUJO PAPER CO LTD (JP) 2008-06-04 CN disclosed
CN-101125303-A Non-agglomerating ion exchange mixed beds LANXESS DEUTSCHLAND GMBH (DE) 2008-02-20 CN disclosed
US-20080009555-A1 Non-agglomerating mixed bed ion exchangers LANXESS DEUTSCHLAND GMBH 2008-01-10 US disclosed
EP-1875965-A2 Non-agglomerating ion exchange mixed beds LANXESS Deutschland GmbH (DE) 2008-01-09 EP disclosed
US-20060252900-A1 (Meth)arcrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained REGENTS OF THE UNIVERSITY OF COLORADO, THE 2006-11-09 US disclosed
CN-1441870-A Printing coated paper JUJO PAPER CO LTD (JP) 2003-09-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230093832-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT CDC37, HSP90B1, CRYAA LMNA 2171/4885TET2 4882/4885TET3 4775/4885
US-20210220266-A1 COMPOSITIONS AND METHODS FOR CONTROLLED RELEASE OF TARGET AGENT IAPP, SCTR, GRPR LMNA 1707/4885TET2 4881/4885TET3 4849/4885
US-20060252900-A1 (Meth)arcrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained MMAB, MAT1A, MAT2A LMNA 4478/4885TET2 24/4885TET3 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.