SCHEMBL4758058

SCHEMBL4758058

C=C(CC=C(O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TET2 Q6N021 5/20 0.37
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM2 Q14416 1/20 0.36
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425600 0.84 ALOX15 (0.38) ALOX15HSD17B10TET2TET3TET1
SCHEMBL8760533 0.79 GRIK1 (0.38) ALOX15HSD17B10TET2TET3TET1
SCHEMBL728395 0.79 TDP1 (0.33) ALDH1A1
SCHEMBL212197 0.77 ALOX15 (0.37) ALOX15HSD17B10TET2TET3TET1
SCHEMBL15017599 0.77 ALOX15 (0.37) ALOX15HSD17B10TET2TET3TET1
SCHEMBL11241202 0.77 ALOX15 (0.47) ALOX15HSD17B10TET2TET3TET1
SCHEMBL11126445 0.77 ALOX15 (0.47) ALOX15HSD17B10TET2TET3TET1
SCHEMBL8948781 0.75 GABRR1 (0.38) ALOX15HSD17B10TET2TET3TET1
SCHEMBL8948783 0.75 GABRR1 (0.38) ALOX15HSD17B10TET2TET3TET1
SCHEMBL664736 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1253134-B1 Vinyl-polymerizable monomer having tertiary hydroxyl group and polymer MITSUBISHI GAS CHEMICAL CO (JP) 2008-11-26 EP disclosed