Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948781 | 1.00 | GABRR1 (0.38) | GABRR1GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL8760533 | 0.81 | GRIK1 (0.38) | GABRR1GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL4758058 | 0.75 | ALOX15 (0.41) | GRIK1GRIK2GRM1GRM2ALOX15 | |
| SCHEMBL10386537 | 0.72 | GRIK1 (0.32) | GRIK1GRIK2GRM1GRM2ALOX15 | |
| SCHEMBL10386536 | 0.72 | GRIK1 (0.32) | GRIK1GRIK2GRM1GRM2ALOX15 | |
| SCHEMBL1425600 | 0.71 | ALOX15 (0.38) | GRIK1GRIK2GRM1GRM2ALOX15 | |
| SCHEMBL728395 | 0.71 | TDP1 (0.33) | — | |
| SCHEMBL212197 | 0.70 | ALOX15 (0.37) | GRIK1GRIK2GRM1GRM2ALOX15 | |
| SCHEMBL15017599 | 0.70 | ALOX15 (0.37) | GRIK1GRIK2GRM1GRM2ALOX15 | |
| SCHEMBL11126445 | 0.69 | ALOX15 (0.47) | GRIK1GRIK2GRM1GRM2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |
| WO-1995005080-A1 | 3-(BICYCLIC HETEROCYCLYL)-6-FLUOROALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |
| US-5346881-A | Herbicides | FMC CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |