Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757429 | 0.90 | PPARG (0.42) | PPARGPPARADRD3MEN1ALDH1A1 | |
| SCHEMBL14311469 | 0.90 | PPARG (0.42) | PPARGPPARADRD3MEN1ALDH1A1 | |
| SCHEMBL4756319 | 0.87 | S1PR1 (0.39) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL4758639 | 0.87 | S1PR1 (0.39) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL4789667 | 0.85 | LTA4H (0.43) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL4789672 | 0.85 | LTA4H (0.43) | PPARGPPARAMEN1ALDH1A1KMT2A | |
| SCHEMBL4755483 | 0.81 | PPARG (0.42) | PPARGPPARADRD3MEN1ALDH1A1 | |
| SCHEMBL4756314 | 0.80 | S1PR5 (0.41) | PPARGPPARAALDH1A1HRH2HRH1 | |
| SCHEMBL4755480 | 0.78 | TEAD1 (0.38) | PPARGPPARAALDH1A1EPHX2HRH3 | |
| SCHEMBL4758435 | 0.78 | TEAD1 (0.48) | PPARGPPARAALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |