Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789672 | 1.00 | LTA4H (0.43) | LTA4HKCNH2ACACBHRH3HRH2 | |
| SCHEMBL4758080 | 0.85 | PPARG (0.41) | LTA4HACACBHRH3HRH2HRH1 | |
| SCHEMBL4755505 | 0.81 | MEN1 (0.45) | ACACBPPARGPPARASMN1; SMN2MEN1 | |
| SCHEMBL4755482 | 0.79 | PPARG (0.47) | ACACBPPARGPPARAMEN1KMT2A | |
| SCHEMBL4758639 | 0.78 | S1PR1 (0.39) | HRH3HRH2HRH1KDM4EPPARG | |
| SCHEMBL4756319 | 0.78 | S1PR1 (0.39) | HRH3HRH2HRH1KDM4EPPARG | |
| SCHEMBL14311458 | 0.77 | HRH2 (0.43) | LTA4HKCNH2HRH3HRH2HRH1 | |
| SCHEMBL4758432 | 0.77 | HRH2 (0.43) | LTA4HKCNH2HRH3HRH2HRH1 | |
| SCHEMBL4756314 | 0.77 | S1PR5 (0.41) | HRH3HRH2HRH1KDM4EPPARG | |
| SCHEMBL4758435 | 0.75 | TEAD1 (0.48) | ACACBHRH2HRH1KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |