Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL4759394 | 0.87 | FAAH (0.38) | SOAT1MEN1KMT2AFAAHTP53 | |
| Monoethanolamine SCHEMBL4758122 | 0.85 | FAAH (0.39) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL28678843 | 0.84 | MEN1 (0.45) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL2869337 | 0.84 | MEN1 (0.45) | SOAT1MEN1KMT2AFAAHTP53 | |
| Monoethanolamine SCHEMBL31070982 | 0.84 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28661833 | 0.83 | MEN1 (0.44) | SOAT1MEN1KMT2AFAAHTP53 | |
| Oleamide SCHEMBL28400601 | 0.79 | FAAH (0.59) | SOAT1MEN1KMT2AFAAHTP53 | |
| Tridecan-1-Ol SCHEMBL28194600 | 0.78 | TSHR (0.43) | MEN1KMT2AGPR84PPARGPPARD | |
| Dodecanol SCHEMBL28381619 | 0.78 | TSHR (0.43) | MEN1KMT2AGPR84PPARGPPARD | |
| Oleamide SCHEMBL25222681 | 0.77 | FAAH (0.60) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866519-B1 | METHOD OF RECYCLING FRACTURING FLUIDS USING A SELF-DEGRADING FOAMING COMPOSITION | RHODIA (US) | 2012-08-08 | — | — | EP | disclosed |
| US-20080200351-A1 | Method of recycling fracturing fluids using a self-degrading foaming composition | DAHANAYAKE MANILAL S | 2008-08-21 | — | — | US | disclosed |
| US-7404442-B2 | Method of recycling fracturing fluids using a self-degrading foaming composition | RHODIA INC. (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1866519-A2 | METHOD OF RECYCLING FRACTURING FLUIDS USING A SELF-DEGRADING FOAMING COMPOSITION | RHODIA INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20060260815-A1 | Method of recycling fracturing fluids using a self-degrading foaming composition | RHODIA OPERATIONS (FR) | 2006-11-23 | — | — | US | disclosed |
| WO-2006108161-A2 | METHOD OF RECYCLING FRACTURING FLUIDS USING A SELF-DEGRADING FOAMING COMPOSITION | RHODIA INC. (US) | 2006-10-12 | — | — | WO | disclosed |