Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.42 |
| ▸ | NT5E | P21589 | 7/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | IARS1 | P41252 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759035 | 0.89 | ADORA3 (0.41) | ADORA3NT5EPDE4DPDE3APNP | |
| SCHEMBL4759053 | 0.86 | ADORA2A (0.49) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL20305241 | 0.85 | ADORA3 (0.46) | ADORA3NT5EPDE4DPDE3APNP | |
| SCHEMBL19961896 | 0.84 | ADORA3 (0.54) | ADORA3NT5EPDE4DPDE3APNP | |
| SCHEMBL4757808 | 0.84 | ADORA3 (0.54) | ADORA3NT5EPDE4DPDE3APNP | |
| SCHEMBL22216550 | 0.84 | ADORA3 (0.54) | ADORA3NT5EPDE4DPDE3APNP | |
| SCHEMBL19948302 | 0.83 | ADORA3 (0.39) | ADORA3NT5EPDE4DPDE3AADORA2A | |
| SCHEMBL19948303 | 0.83 | ADORA3 (0.39) | ADORA3NT5EPDE4DPDE3AADORA2A | |
| SCHEMBL20337513 | 0.83 | ADORA3 (0.39) | ADORA3NT5EPDE4DPDE3AADORA2A | |
| SCHEMBL5963251 | 0.81 | STING1 (0.38) | ADORA3NT5EADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342003-B2 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342003-B2 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| US-20060135466-A1 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135466-A1 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | ADA, ADAR, DCTD | ADORA3 44/4885NT5E 157/4885PDE4D 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.