Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757779 | 0.83 | HDAC3 (0.44) | DDR1SMN1; SMN2MEN1KMT2AMGLL | |
| SCHEMBL4758236 | 0.82 | DDR1 (0.34) | DDR1NOTUMHRH3KDM4E | |
| SCHEMBL4755128 | 0.82 | MAPK14 (0.44) | DDR1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL4758284 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL28818662 | 0.69 | HDAC1 (0.42) | SMN1; SMN2KDM4EP2RY12 | |
| SCHEMBL2942517 | 0.69 | NOTUM (0.51) | WDR91NOTUMCHRM1MGLL | |
| SCHEMBL3100227 | 0.69 | ATM (0.55) | NOTUMSMN1; SMN2 | |
| SCHEMBL4755723 | 0.68 | CSF1R (0.48) | DDR1KDM4E | |
| SCHEMBL3508055 | 0.68 | HSD17B10 (0.44) | WDR91NOTUMCHRM5CHRM1HPGD | |
| SCHEMBL382520 | 0.67 | TDP1 (0.54) | SMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |