Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 7/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 6/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758264 | 0.82 | WDR91 (0.40) | DDR1KDM4EHRH3NOTUM | |
| SCHEMBL4755128 | 0.77 | MAPK14 (0.44) | DDR1KCNH2KDM4E | |
| SCHEMBL4757779 | 0.76 | HDAC3 (0.44) | DDR1 | |
| SCHEMBL4758284 | 0.68 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL21430984 | 0.68 | JAK3 (0.37) | KDM4E | |
| SCHEMBL4755723 | 0.66 | CSF1R (0.48) | DDR1KDM4E | |
| SCHEMBL30461098 | 0.65 | HCRTR1 (0.42) | KDM4EHRH3 | |
| SCHEMBL7082922 | 0.65 | ACACB (0.43) | ACACB | |
| SCHEMBL30807534 | 0.64 | GPR119 (0.39) | ACACB | |
| SCHEMBL26760872 | 0.64 | LIPG (0.36) | ACACBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |