Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242486 | 0.81 | PPARG (0.42) | PPARG | |
| SCHEMBL13619509 | 0.81 | PPARG (0.42) | PPARG | |
| SCHEMBL3857652 | 0.77 | PPARG (0.45) | PPARG | |
| SCHEMBL7061672 | 0.73 | PPARG (0.51) | PPARG | |
| SCHEMBL6955527 | 0.72 | CASP1 (0.60) | CASP1 | |
| SCHEMBL6156731 | 0.72 | CASP1 (0.60) | CASP1 | |
| SCHEMBL6156740 | 0.72 | CASP1 (0.60) | CASP1 | |
| SCHEMBL4359028 | 0.72 | PPARG (0.41) | PPARG | |
| SCHEMBL4359031 | 0.72 | PPARG (0.41) | PPARG | |
| SCHEMBL4359035 | 0.72 | PPARG (0.41) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971582-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |