Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955527 | 0.80 | CASP1 (0.60) | — | |
| SCHEMBL6156731 | 0.80 | CASP1 (0.60) | — | |
| SCHEMBL6156740 | 0.80 | CASP1 (0.60) | — | |
| SCHEMBL3857870 | 0.79 | CASP1 (0.51) | — | |
| SCHEMBL7063847 | 0.76 | PPARG (0.50) | PPARGMGLL | |
| SCHEMBL3863275 | 0.75 | HTT (0.54) | — | |
| SCHEMBL3863271 | 0.75 | HTT (0.54) | — | |
| SCHEMBL6677862 | 0.75 | CASP1 (0.43) | — | |
| SCHEMBL14562401 | 0.75 | KLK1 (0.57) | — | |
| SCHEMBL3857652 | 0.74 | PPARG (0.45) | PPARGMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617332-B1 | Cyclic amidinourea derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | disclosed |