Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 18/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14559468 | 0.98 | MAOA (0.65) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6071169 | 0.93 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5407026 | 0.93 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4757630 | 0.92 | MAOA (0.65) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5410743 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5415678 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6071596 | 0.92 | MAOA (0.60) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559469 | 0.92 | MAOA (0.63) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6070815 | 0.91 | MAOA (0.70) | MAOACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14559473 | 0.91 | MAOA (0.62) | MAOACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599471-B1 | HYDROXYMETHYL SUBSTITUTED DIHYDROISOXAZOLE DERIVATIVES USEFUL AS ANTIBIOTIC AGENTS | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | EP | disclosed |
| US-7192974-B2 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |
| US-20060270637-A1 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270637-A1 | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents | RPS7, CYP3A7, CYP2A7 | MAOA 1154/4885CYP3A4 123/4885CYP2D6 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.