Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18920800 | 0.92 | KDM4E (0.56) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL4790603 | 0.87 | CHRM2 (0.58) | CHRM2SIRT2KDM4EALDH1A1GRIN2D | |
| SCHEMBL8508355 | 0.85 | ALDH1A1 (0.48) | CHRM2KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL30894457 | 0.84 | CHRM2 (0.62) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL348655 | 0.82 | CHRM2 (0.78) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL3071526 | 0.80 | CHRM2 (0.81) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL284677 | 0.80 | CHRM2 (0.81) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9702944 | 0.78 | CHRM2 (0.79) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9777412 | 0.78 | CHRM2 (0.79) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3626828 | 0.78 | CHRM2 (0.79) | CHRM2SIRT2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021788-A2 | POLYAMINE COMPOUNDS | TAIGEN BIOTECHNOLOGY CO., LTD. (CN) | 2008-02-21 | — | — | WO | disclosed |