Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106415 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL4402023 | 0.83 | ADRB2 (0.44) | SMN1; SMN2ADRB2ADRB1ADRB3SCN1A | |
| SCHEMBL3106421 | 0.83 | ADRB2 (0.44) | SMN1; SMN2ADRB2ADRB1ADRB3SCN1A | |
| SCHEMBL4758614 | 0.81 | TSHR (0.43) | SMN1; SMN2ADRB2ADRB1ADRB3SCN1A | |
| SCHEMBL17797889 | 0.79 | ALDH1A1 (0.62) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL15110945 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL17797803 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL29674421 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL17797818 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL16048344 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2ADRB2ADRB1ADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | disclosed |