Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.41 |
| ▸ | CASR | P41180 | 5/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105648 | 0.78 | CCR5 (0.40) | CASRCCR5CYP2D6 | |
| SCHEMBL4758707 | 0.75 | CCR5 (0.39) | CCR5 | |
| SCHEMBL4100917 | 0.73 | CASR (0.47) | CASR | |
| SCHEMBL4104683 | 0.73 | CASR (0.50) | CASRCCR5CYP2D6 | |
| SCHEMBL3573546 | 0.73 | CASR (0.39) | SSTR4CASRCYP2D6 | |
| SCHEMBL4102217 | 0.73 | CASR (0.49) | CASRCCR5CYP2D6 | |
| SCHEMBL4099302 | 0.72 | CASR (0.47) | CASRCYP2D6 | |
| SCHEMBL4099293 | 0.72 | CASR (0.47) | CASRCYP2D6 | |
| Hydrochloric Acid SCHEMBL4100877 | 0.72 | CASR (0.49) | CASR | |
| Hydrochloric Acid SCHEMBL4106149 | 0.72 | CASR (0.49) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882684-A1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-01-30 | — | — | EP | disclosed |