SCHEMBL475876

SCHEMBL475876

COC(=O)/C=C\C(=O)O[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.56
HCAR2 Q8TDS4 3/20 0.56
KEAP1 Q14145 1/20 0.56
GFPT1 Q06210 1/20 0.37
ALDH1A1 P00352 5/20 0.35
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
TYR P14679 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475877 1.00 NFE2L2 (0.56) NFE2L2HCAR2KEAP1GFPT1ALDH1A1
SCHEMBL475995 1.00 NFE2L2 (0.56) NFE2L2HCAR2KEAP1GFPT1ALDH1A1
SCHEMBL5974692 0.91 HCAR2 (0.39) NFE2L2HCAR2KEAP1
SCHEMBL5974208 0.91 HCAR2 (0.39) NFE2L2HCAR2KEAP1
SCHEMBL5974213 0.91 HCAR2 (0.39) NFE2L2HCAR2KEAP1
SCHEMBL17529807 0.83 HCAR2 (0.54) NFE2L2HCAR2KEAP1ALDH1A1MAPT
SCHEMBL17529809 0.83 HCAR2 (0.54) NFE2L2HCAR2KEAP1ALDH1A1MAPT
SCHEMBL4642002 0.81 HCAR2 (0.45) NFE2L2HCAR2KEAP1GFPT1ALDH1A1
SCHEMBL2144200 0.80 HCAR2 (0.48) NFE2L2HCAR2KEAP1GFPT1ALDH1A1
SCHEMBL4642335 0.80 HCAR2 (0.43) NFE2L2HCAR2KEAP1GFPT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
EP-4617318-A1 RESIN COMPOSITION AND MOLDED BODY MCPP Innovation LLC (JP) 2025-09-17 EP disclosed
US-20250257215-A1 RESIN COMPOSITION AND MOLDED ARTICLE MCPP INNOVATION LLC (JP) 2025-08-14 US disclosed
EP-4299684-B1 ANTIFOULING COATING COMPOSITION AND COATING FILM NIPPON PAINT MARINE COATINGS CO LTD (JP) 2025-03-05 EP disclosed
CN-109952328-B (Meth) acrylic copolymer, coating composition, coated article, and method for forming multilayer coating film 三菱化学株式会社 2025-01-14 CN disclosed
CN-117480220-B Antifouling paint composition and coating film 日本油漆船舶涂料公司 2024-10-18 CN disclosed
CN-118159603-A Resin composition, method for producing resin composition, molding material, and article 三菱化学株式会社 2024-06-07 CN disclosed
US-20240174864-A1 ACRYLIC RESIN EMULSION, PRODUCTION METHOD THEREFOR, AND COATING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-30 US disclosed
EP-1208167-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2002-05-29 EP disclosed
WO-2000077102-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2000-12-21 WO disclosed
US-5767171-A A MARINE, HYDROLYZABLE, ANTIFOULING, PROTECTIVE COATING BASED ON A POLYMER OF A TRIALKYLSILYL (METH)ACRYLATE AND AN ALKYLOXYALKYL (METH)ACRYLATE; NONCRACKING; UNIFORM EROSION; ADHESION NOF CORPORATION (JP) 1998-06-16 US disclosed
EP-0714957-B1 Hydrolyzable self-polishing coating composition NOF CORP (JP) 1998-03-04 EP disclosed
EP-0646630-B1 Antifouling coating composition NOF CORP (JP) 1997-04-23 EP disclosed
EP-0714957-A1 Hydrolyzable self-polishing coating composition NOF CORPORATION (JP) 1996-06-05 EP disclosed
US-5436284-A Preventing attachment of organisms to surfaces of structures submerged in seawater NOF CORPORATION (JP) 1995-07-25 US disclosed
EP-0646630-A1 Antifouling coating composition NOF CORPORATION (JP) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 NFE2L2 3335/4885HCAR2 325/4885KEAP1 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.