SCHEMBL4758991

SCHEMBL4758991

CC(C)(C)Oc1ccc(C(C)(C)c2ccc(OP(C)(=O)Oc3ccc(C(C)(C)c4ccc(OC(=O)C(C)(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ELANE P08246 17/20 0.47
PRTN3 P24158 3/20 0.38
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13932017 0.89 ELANE (0.59) ELANEPRTN3ALDH1A1
SCHEMBL15429254 0.85 ELANE (0.43) ELANEPRTN3ALDH1A1KDM4EMEN1
SCHEMBL24667224 0.81 ELANE (0.70) ELANEPRTN3ALDH1A1
SCHEMBL17678829 0.81 ELANE (0.70) ELANEPRTN3
SCHEMBL18774620 0.79 ESR1 (0.47) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL16672004 0.78 ESR1 (0.57) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL15946722 0.78 ESR1 (0.57) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL16677059 0.76 ELANE (0.63) ELANEPRTN3ALDH1A1
SCHEMBL19557785 0.76 ELANE (0.81) ELANEPRTN3ALDH1A1KDM4EMEN1
SCHEMBL19020532 0.76 ELANE (0.69) ELANEPRTN3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180187084-A1 CURING OF EPOXY RESINS WITH PHOSPHONATE OLIGOMERS FRX POLYMERS, INC. 2018-07-05 US disclosed
US-20180155541-A1 POLYMER RESINS WITH PHOSPHONATE OLIGOMERS FRX POLYMERS, INC. 2018-06-07 US disclosed
US-20170190876-A1 FAST CURING, TRANSPARENT AND TRANSLUCENT, NON-HALOGENATED FLAME RETARDANT SYSTEMS FRX POLYMERS, INC. 2017-07-06 US disclosed
US-20160244607-A1 FLAME RETARDANT THERMOSET COMPOSITIONS FRX POLYMERS, INC. 2016-08-25 US disclosed
US-20160168760-A1 PHOSPHONATE POLYMERS, COPOLYMERS, AND THEIR RESPECTIVE OLIGOMERS AS FLAME RETARDANTS FOR POLYESTER FIBERS FRX POLYMERS, INC. 2016-06-16 US disclosed
US-20160160041-A1 FLAME RETARDANT THERMOPLASTIC AND THERMOSET COMPOSITIONS FRX POLYMERS, INC. (US) 2016-06-09 US disclosed
US-9290653-B2 Phosphonate polymers, copolymers, and their respective oligomers as flame retardants for polyester fibers FRX POLYMERS, INC. (US) 2016-03-22 US disclosed
US-20150252228-A1 EPOXY COMPOSITIONS FRX POLYMERS, INC. (US) 2015-09-10 US disclosed
US-20150252175-A1 EPOXY COMPOSITIONS FRX POLYMERS, INC. (US) 2015-09-10 US disclosed
US-20150105484-A1 FLAME RETARDANT THERMOPLASTIC ELASTOMERS FOR EXTRUSION OR INJECTION MOLDING FRX POLYMERS, INC. 2015-04-16 US disclosed
US-20140308505-A1 PHOSPHONATE POLYMERS, COPOLYMERS, AND THEIR RESPECTIVE OLIGOMERS AS FLAME RETARDANTS FOR POLYAMIDE FIBERS SCHMITT THOMAS EDWARD (US) 2014-10-16 US disclosed
US-8563638-B2 Oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-10-22 US disclosed
US-8530044-B2 Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-09-10 US disclosed
US-20120171460-A1 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US disclosed
US-20120172500-A1 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US disclosed
US-20120121843-A1 PHOSPHONATE POLYMERS, COPOLYMERS, AND THEIR RESPECTIVE OLIGOMERS AS FLAME RETARDANTS FOR POLYESTER FIBERS FRX POLYMERS, INC. (US) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180187084-A1 CURING OF EPOXY RESINS WITH PHOSPHONATE OLIGOMERS PFAS, PHOSPHO1, PPA1 ELANE 415/4885PRTN3 2128/4885ALDH1A1 2281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.