Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863346 | 0.78 | HTR1D (0.33) | DUT | |
| SCHEMBL3856653 | 0.74 | HTR1D (0.31) | DUT | |
| SCHEMBL7559276 | 0.71 | DUT (0.37) | DUT | |
| SCHEMBL8545478 | 0.70 | DUT (0.36) | DUT | |
| SCHEMBL2194607 | 0.69 | DUT (0.30) | DUT | |
| SCHEMBL5790573 | 0.69 | DUT (0.33) | DUT | |
| SCHEMBL28571277 | 0.69 | DUT (0.33) | DUT | |
| SCHEMBL2696466 | 0.68 | CYP1A2 (0.41) | DUT | |
| SCHEMBL14665868 | 0.68 | DUT (0.35) | DUT | |
| SCHEMBL11580466 | 0.67 | DUT (0.42) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971582-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |