Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185281 | 0.81 | IDO1 (0.42) | DUT | |
| SCHEMBL4225544 | 0.81 | BACE1 (0.32) | DUT | |
| SCHEMBL3403690 | 0.81 | DUT (0.43) | DUT | |
| SCHEMBL10596180 | 0.81 | — | — | |
| SCHEMBL28571277 | 0.80 | DUT (0.33) | DUT | |
| SCHEMBL2027168 | 0.80 | LOXL2 (0.41) | DUT | |
| SCHEMBL2696466 | 0.80 | CYP1A2 (0.41) | DUT | |
| SCHEMBL24197444 | 0.79 | TAAR1 (0.44) | — | |
| SCHEMBL2366928 | 0.79 | GFER (0.45) | DUT | |
| SCHEMBL1245973 | 0.79 | ELOVL1 (0.41) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771025-B | Deuterated compounds as ROCK inhibitors | 重庆复创医药研究有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-112771025-A | Deuterated compounds as ROCK inhibitors | 重庆复创医药研究有限公司 | 2021-05-07 | — | — | CN | disclosed |
| EP-0659747-B1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-04-01 | — | — | EP | disclosed |
| EP-0659747-A1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-06-28 | — | — | EP | disclosed |