⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472856 | 0.84 | — | — | |
| SCHEMBL3428398 | 0.83 | — | — | |
| SCHEMBL9120605 | 0.83 | — | — | |
| SCHEMBL5226040 | 0.82 | FDPS (0.43) | — | |
| SCHEMBL4574427 | 0.82 | ALDH1A1 (0.47) | — | |
| SCHEMBL5043060 | 0.82 | FDPS (0.43) | — | |
| SCHEMBL2398675 | 0.81 | — | — | |
| SCHEMBL11304738 | 0.81 | — | — | |
| SCHEMBL15573121 | 0.81 | FDPS (0.46) | — | |
| SCHEMBL15572413 | 0.81 | FDPS (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874478-A | Food spice compound and application thereof | 宁夏信达昌科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-115491700-B | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115491700-A | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-110643430-A | Mushroom flavor essence formula | 武穴格莱默生物科技有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-109294736-A | A kind of mushroom taste composition | 双凯食品配料（昆山）有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-116874478-A | Food spice compound and application thereof | 宁夏信达昌科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| CN-115491700-B | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115491700-B | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115491700-B | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115491700-A | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-115491700-A | Electrochemical synthesis method of spice 2-propionyl thiazole | 济南悟通生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| EP-0788497-A1 | BISARYLCARBINOL DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1997-08-13 | — | — | EP | disclosed |
| EP-0788490-A1 | BISARYLCARBINOL CINNAMIC ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1997-08-13 | — | — | EP | disclosed |
| US-5552437-A | ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY, AND CYTOPROTECTIVE AGENTS | MERCK FROSST CANADA, INC. (CA) | 1996-09-03 | — | — | US | disclosed |
| US-5527827-A | ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS | MERCK FROSST CANADA, INC. (CA) | 1996-06-18 | — | — | US | disclosed |
| WO-1996013491-A1 | BISARYLCARBINOL CINNAMIC ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1996-05-09 | — | — | WO | disclosed |
| WO-1996013500-A1 | BISARYLCARBINOL DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1996-05-09 | — | — | WO | disclosed |
| EP-0146797-B1 | 2-AMINOTHIOPHENE COMPOUNDS | BAYER AG (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0146797-A1 | 2-Aminothiophene compounds | BAYER AG (DE) | 1985-07-03 | — | — | EP | disclosed |