Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.42 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044534 | 1.00 | THRB (0.55) | THRBTSHRCHRM1CHRM3CHRM2 | |
| Bromide SCHEMBL4541172 | 0.98 | THRB (0.53) | THRBTSHRCHRM1CHRM3CHRM2 | |
| Iodide SCHEMBL2281650 | 0.98 | THRB (0.53) | THRBTSHRCHRM1CHRM3CHRM2 | |
| Sulfuric Acid SCHEMBL7201069 | 0.91 | THRB (0.47) | THRBTSHRCHRM1CHRM3CHRM2 | |
| Phosphoric Acid SCHEMBL7193071 | 0.91 | TSHR (0.50) | THRBTSHRCHRM1CHRM3CHRM2 | |
| SCHEMBL16353002 | 0.91 | TSHR (0.53) | THRBTSHRCHRM1CHRM3CHRM2 | |
| SCHEMBL13109193 | 0.91 | THRB (0.50) | THRBTSHRCHRM1CHRM3CHRM2 | |
| SCHEMBL23375504 | 0.89 | TSHR (0.56) | THRBTSHRCHRM1CHRM3CHRM2 | |
| Bromide SCHEMBL4952804 | 0.89 | TSHR (0.51) | THRBTSHRCHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL475736 | 0.89 | TSHR (0.59) | THRBTSHRCHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114351460-B | Fiber material with antibacterial function, preparation method thereof and fiber product thereof | 广州弘海材料科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-114276488-B | Long-chain branch multi-head cationic polyacrylamide and application thereof | 河南博源新材料有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-111909069-B | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114351460-A | Fiber material with antibacterial function, preparation method thereof and fiber product thereof | 广州弘海材料科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-114276488-A | Long-chain branch multi-head cationic polyacrylamide and application thereof | 河南博源新材料有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111909069-A | Degradable quaternary ammonium salt compound and preparation method and application thereof | 安徽启威生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| EP-2964827-B1 | VENTILATION INSERT | FREUDENBERG CARL KG (DE) | 2019-11-06 | — | — | EP | claimed |
| CN-105085822-A | Sludge-proof type polycarboxylate water-reducer and normal temperature preparing method thereof | KEZHIJIE NEW MATERIALS GROUP CO LTD | 2015-11-25 | — | — | CN | claimed |
| US-8771716-B2 | Modified release analgesic suspensions | MCNEIL-PPC, INC. (US) | 2014-07-08 | — | — | US | claimed |
| US-20130142846-A1 | Modified Release Analgesic Suspensions | MCNEIL-PPC, INC (US) | 2013-06-06 | — | — | US | claimed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | claimed |
| US-20060204952-A1 | Technique for measuring cell-membrane properties in cultured cells grown on biomaterials in an Ussing chamber | IOWA RESEARCH FOUNDATION | 2006-09-14 | — | — | US | claimed |
| US-4788242-A | Polyvinyl alcohol-based reversibly hydrated gel, highly water-absorptive resin and method for the preparation thereof | SHIN-ESTU CHEMICAL CO., LTD. (JP) | 1988-11-29 | — | — | US | claimed |
| US-4439322-A | IONIC COPOLYMER | TORAY INDUSTRIES, INC. (JP) | 1984-03-27 | — | — | US | claimed |
| JP-59126418-A | — | — | None | — | — | JP | disclosed |
| JP-1167305-A | — | — | None | — | — | JP | disclosed |
| US-12630728-B2 | Ink set and recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| JP-S59126418-A | RESIN COMPOSITION FOR AQUEOUS DISPERSION | JAPAN ATOM ENERGY RES INST | 1984-07-21 | — | — | JP | disclosed |
| US-4439322-A | IONIC COPOLYMER | TORAY INDUSTRIES, INC. (JP) | 1984-03-27 | — | — | US | disclosed |
| US-4105510-A | POLYMER OR COPOLYMER OF AN ACRYLAMIDE AND/OR A QUATERNARY AMMONIUM SALT OF A DIALKYLAMINOALKYL ACRYLATE; ADDING A POLYHYDRIC PHENOL, BENZOQUINONE OR DERIVATIVES | KYORITSU YUKI CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630728-B2 | Ink set and recording method | DOT1L, SET, ALKBH3 | CHRM1 626/4885CHRM3 260/4885CHRM2 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.