SCHEMBL4759488

SCHEMBL4759488

C1=Nc2c(ccc3cccnc23)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.48
KDM4E B2RXH2 4/20 0.48
MAPT P10636 4/20 0.48
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
TSHR P16473 3/20 0.48
MMP2 P08253 2/20 0.48
HTT P42858 2/20 0.48
GMNN O75496 1/20 0.48
TP53 P04637 1/20 0.48
HSP90AA1 P07900 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
MMP9 P14780 1/20 0.48
ALOX15 P16050 1/20 0.48
NFKB1 P19838 1/20 0.48
MMP8 P22894 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249744 0.75 MAPT (0.50) LMNAKDM4EMAPTTSHRHTT
SCHEMBL22073253 0.74 KDM4E (0.42) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL22664091 0.73 LMNA (0.48) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL23676649 0.72 CCR1 (0.47) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL19786094 0.72 CCR1 (0.35) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL22099513 0.71 KDM4E (0.46) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL15388979 0.71 LMNA (0.46) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL22540186 0.70 LMNA (0.44) LMNAKDM4EMAPTCCR1CCR5
SCHEMBL23585497 0.69 TSHR (0.34) KDM4EMAPTTSHRCYP3A4ALDH1A1
SCHEMBL23585234 0.69 ALDH1A1 (0.38) KDM4EMAPTTSHRCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1372269-A Conductive pasty material, method for controlling its viscosity and electronic component using same MURATA MANUFACTURING CO (JP) 2002-10-02 CN claimed
EP-0698226-A4 COMPLEMENTARY SURFACE CONFINED POLYMER ELECTROCHROMIC MATERIALS, SYSTEMS, AND METHODS OF FABRICATION THEREFOR IGEN INC (US) 1997-02-12 EP claimed
EP-0698226-A1 COMPLEMENTARY SURFACE CONFINED POLYMER ELECTROCHROMIC MATERIALS, SYSTEMS, AND METHODS OF FABRICATION THEREFOR IGEN, INCORPORATED (US) 1996-02-28 EP claimed
CN-117843689-A Organometallic compound, organic light emitting diode having the same, and organic light emitting device 乐金显示有限公司 2024-04-09 CN disclosed
EP-4143249-A1 PROCESS FOR PREPARING OLEFIN-ACRYLATE BLOCK COPOLYMERS BY ATRP Dow Global Technologies LLC (US) 2023-03-08 EP disclosed
CN-115057868-A Preparation method of thieno [2,3-b ] thiophene 中原工学院 2022-09-16 CN disclosed
CN-109180567-B Nitrogen heterocyclic compound, display panel and display device 武汉天马微电子有限公司 2022-05-20 CN disclosed
WO-2021222655-A1 PROCESS FOR PREPARING OLEFIN-ACRYLATE BLOCK COPOLYMERS BY ATRP DOW GLOBAL TECHNOLOGIES LLC (US) 2021-11-04 WO disclosed
EP-3239157-B1 NOVEL GROUP 4 TRANSITION METAL COMPOUND AND USE THEREOF HANWHA CHEMICAL CORP (KR) 2021-09-29 EP disclosed
WO-2021135207-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
CN-107001500-B Novel group 4 transition metal compound and use thereof 韩华化学株式会社 2020-11-03 CN disclosed
US-20040176534-A1 Polymers and their synthesis Henkel IP & Holding GmbH (DE) 2004-09-09 US disclosed
US-20040171513-A1 Use of graft polymers in fabric cleaning Henkel IP & Holding GmbH (DE) 2004-09-02 US disclosed
EP-1263599-A1 ANTI-COUNTERFEITING DEVICE SCIENTIFIC GENERICS LIMITED (GB) 2002-12-11 EP disclosed
CN-1372269-A Conductive pasty material, method for controlling its viscosity and electronic component using same MURATA MANUFACTURING CO (JP) 2002-10-02 CN disclosed
WO-2001053106-A1 ANTI-COUNTERFEITING DEVICE SCIENTIFIC GENERICS LIMITED (GB) 2001-07-26 WO disclosed
WO-2001017997-A1 SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY DIAZANS LIMITED (CA) 2001-03-15 WO disclosed
EP-0698226-A4 COMPLEMENTARY SURFACE CONFINED POLYMER ELECTROCHROMIC MATERIALS, SYSTEMS, AND METHODS OF FABRICATION THEREFOR IGEN INC (US) 1997-02-12 EP disclosed
EP-0698226-A1 COMPLEMENTARY SURFACE CONFINED POLYMER ELECTROCHROMIC MATERIALS, SYSTEMS, AND METHODS OF FABRICATION THEREFOR IGEN, INCORPORATED (US) 1996-02-28 EP disclosed
US-4300011-A FROM HYDROCARBONS USING ZEOLITE CATALYSTS AND HETEROCYCLE ORGANIC NITROGEN COMPOUNDS MOBIL OIL CORPORATION (US) 1981-11-10 US disclosed