Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459465 | 1.00 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4759732 | 1.00 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL2882981 | 1.00 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5459468 | 1.00 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6826523 | 0.86 | SLC6A3 (0.54) | SLC6A3 | |
| SCHEMBL3436817 | 0.85 | MEN1 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3832793 | 0.84 | SLC6A3 (0.72) | SLC6A3 | |
| SCHEMBL3833873 | 0.84 | SLC6A3 (0.72) | SLC6A3 | |
| SCHEMBL1944023 | 0.84 | SLC6A3 (0.52) | SLC6A3 | |
| SCHEMBL7812342 | 0.84 | SLC6A3 (0.72) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966137-A2 | PIPERIDINE DERIVATIVES | Pfizer Products Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007072150-A2 | PIPERIDINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| US-20070142389-A1 | PIPERIDINE DERIVATIVES | PFIZER INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142389-A1 | PIPERIDINE DERIVATIVES | CFTR, HDAC10, RPP30 | SLC6A3 2127/4885SLC6A2 2730/4885SLC6A4 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.