SCHEMBL475980

SCHEMBL475980

CC(=O)OC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
PTGS1 P23219 1/20 0.61
XIAP P98170 1/20 0.61
SLC7A5 Q01650 1/20 0.61
SLC15A1 P46059 2/20 0.53
ALDH1A1 P00352 1/20 0.52
LTA4H P09960 1/20 0.50
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
HDAC8 Q9BY41 2/20 0.47
SRR Q9GZT4 1/20 0.47
SLC6A2 P23975 2/20 0.47
TAAR1 Q96RJ0 2/20 0.47
MAOA P21397 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CYP2A6 P11509 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13087400 1.00 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5547318 1.00 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8835936 0.91 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL288607 0.91 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28820471 0.91 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29160724 0.89 SLC7A5 (0.66) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL10914203 0.88 FFAR1 (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8609126 0.87 SLC7A5 (0.63) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1526409 0.87 ALPI (0.63) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27232046 0.87 ALPI (0.63) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3337456-B1 LIPOSOMES WITH GINSENOSIDE AS MEMBRANE MATERIAL AND PREPARATIONS AND USE THEREOF SHANGHAI GINPOSOME PHARMATECH CO LTD (CN) 2022-10-26 EP claimed
EP-3773910-A1 HUMANIZED ANTI-PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) ANTIBODY DRUG CONJUGATES Ambrx, Inc. (US) 2021-02-17 EP claimed
US-10639276-B2 Liposomes with ginsenoside as membrane material and preparations and use thereof SHANGHAI GINPOSOME PHARMATECH CO., LTD. (CN) 2020-05-05 US claimed
CN-110885404-A Synthesis method of active bagasse xylan acetyl phenylalanine ester-g-VAc 桂林理工大学 2020-03-17 CN claimed
WO-2019191728-A1 HUMANIZED ANTI-PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) ANTIBODY DRUG CONJUGATES AMBRX, INC. (US) 2019-10-03 WO claimed
EP-3463415-A1 AQUEOUSLY SOLUBLE & CHEMICALLY STABLE GLUCAGON PEPTIDES Indiana University Research & Technology Corporation (US) 2019-04-10 EP claimed
EP-3463423-A1 GLUCAGON-T3 CONJUGATES Indiana University Research & Technology Corporation (US) 2019-04-10 EP claimed
US-10232020-B2 Incretin-insulin conjugates INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2019-03-19 US claimed
EP-3337456-A1 LIPOSOMES WITH GINSENOSIDE AS MEMBRANE MATERIAL AND PREPARATIONS AND USE THEREOF Shanghai Ginposome Pharmatech Co., Ltd. (CN) 2018-06-27 EP claimed
EP-2780031-B1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY UNIV INDIANA RES & TECH CORP (US) 2018-03-07 EP claimed
EP-1836298-A4 COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF AMBRX INC (US) 2008-07-09 EP claimed
EP-1937824-A1 COMPOSITIONS OF tRNA AND USES THEREOF Ambrx, Inc. (US) 2008-07-02 EP claimed
EP-1836298-A2 COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF AMBRX, INC. (US) 2007-09-26 EP claimed
WO-2007021297-A1 COMPOSITIONS OF tRNA AND USES THEREOF AMBRX, INC. (US) 2007-02-22 WO claimed
WO-2006068802-A2 COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF AMBRX, INC. (US) 2006-06-29 WO claimed
US-5688913-A OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS CYTEL CORPORATION (US) 1997-11-18 US claimed
US-5519000-A OLIGOPEPTIDE CENTECOR, INC. (US) 1996-05-21 US claimed
WO-1995026744-A1 TUMOR NECROSIS FACTOR INHIBITORS CENTOCOR, INC. (US) 1995-10-12 WO claimed
CN-1091952-A Cosmetic composition UNILEVER NV (NL) 1994-09-14 CN claimed
EP-0203031-B1 BIOLOGICALLY ACTIVE LYSINE CONTAINING OCTAPEPTIDES The Administrators of The Tulane University Educational Fund (US) 1992-07-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10639276-B2 Liposomes with ginsenoside as membrane material and preparations and use thereof SGMS1, LIPA, SGMS2 ALPI 1642/4885PKM 2634/4885PTGS1 222/4885
US-10232020-B2 Incretin-insulin conjugates GPR119, GLP1R, GIPR ALPI 571/4885PKM 4013/4885PTGS1 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.