SCHEMBL475983

SCHEMBL475983

[CH2]C(=O)O[Si](C)(C)CCCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.35
CES2 O00748 4/20 0.34
CES1 P23141 4/20 0.34
TSHR P16473 3/20 0.33
AKR1B1 P15121 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NAAA Q02083 1/20 0.32
DGKA P23743 1/20 0.32
FAAH O00519 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
SLC22A8 Q8TCC7 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475986 0.98 EPHX1 (0.38) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL476207 0.98 EPHX1 (0.38) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL475911 0.98 EPHX1 (0.38) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL476008 0.98 EPHX1 (0.38) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL475847 0.98 EPHX1 (0.38) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL476045 0.94 LMNA (0.33) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL1408623 0.85
SCHEMBL28662471 0.81 AKR1B1 (0.39) EPHX1CES2CES1TSHRAKR1B1
SCHEMBL28664047 0.81 EPHX1 (0.41) EPHX1CES2CES1TSHRALDH1A1
SCHEMBL475989 0.81 EPHX1 (0.36) EPHX1CES2CES1TSHRAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2173780-B1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN AS (NO) 2012-05-23 EP disclosed
EP-2294148-B1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN AS (NO) 2012-02-01 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-20110123478-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2011-05-26 US disclosed
EP-2173780-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER Jotun A/S (NO) 2010-04-14 EP disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed