SCHEMBL475989

SCHEMBL475989

[CH2]C(=O)O[Si](CCCCC)(CCCCC)CCCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.36
CES2 O00748 4/20 0.36
CES1 P23141 4/20 0.36
AKR1B1 P15121 1/20 0.34
TSHR P16473 5/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
PPARG P37231 4/20 0.33
PPARD Q03181 4/20 0.33
PPARA Q07869 4/20 0.33
GPR84 Q9NQS5 3/20 0.33
HDAC11 Q96DB2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
TLR2 O60603 1/20 0.33
NAAA Q02083 1/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475935 0.98 EPHX1 (0.39) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL476141 0.98 EPHX1 (0.39) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL475991 0.98 EPHX1 (0.39) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL475930 0.93 ACHE (0.33) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL476032 0.84 TDP1 (0.30) TDP1
SCHEMBL475983 0.81 EPHX1 (0.35) EPHX1CES2CES1AKR1B1TSHR
SCHEMBL475990 0.80 ALDH1A1 (0.43) EPHX1CES2CES1AKR1B1TSHR
SCHEMBL4642348 0.79 NAAA (0.35) EPHX1CES2CES1TSHRNAAA
SCHEMBL475911 0.79 EPHX1 (0.38) EPHX1CES2CES1TSHRZDHHC20
SCHEMBL5838837 0.79 TSHR (0.53) EPHX1CES2CES1AKR1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2173780-B1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN AS (NO) 2012-05-23 EP disclosed
EP-2294148-B1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN AS (NO) 2012-02-01 EP disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-20110123478-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2011-05-26 US disclosed
EP-2294148-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER Jotun A/S (NO) 2011-03-16 EP disclosed
EP-2173780-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER Jotun A/S (NO) 2010-04-14 EP disclosed
WO-2009149919-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2009-12-17 WO disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed