Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324527 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTHSP90AA1CCR6NPSR1 | |
| SCHEMBL27877227 | 0.81 | ALDH1A1 (0.32) | ALDH1A1MAPTHSP90AA1CCR6NPSR1 | |
| SCHEMBL223853 | 0.74 | MAPT (0.42) | ALDH1A1MAPTNPSR1KDM4ENOTUM | |
| SCHEMBL22994399 | 0.72 | L3MBTL1 (0.46) | ALDH1A1MAPTHSP90AA1NPSR1NOTUM | |
| SCHEMBL34512 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPTNPSR1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL820585 | 0.72 | MAPT (0.41) | ALDH1A1MAPTNPSR1KDM4ENOTUM | |
| SCHEMBL28250871 | 0.70 | MAPT (0.34) | ALDH1A1MAPTHSP90AA1CCR6NPSR1 | |
| Hydrochloric Acid SCHEMBL552835 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPTNPSR1KDM4EPOLB | |
| Iodide SCHEMBL28719252 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPTNPSR1KDM4EPOLB | |
| Bromide SCHEMBL30353850 | 0.70 | ALDH1A1 (0.34) | ALDH1A1MAPTNPSR1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361922-B2 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | MATERIA, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120123133-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123133-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | ORC3, OXER1, CBR3 | ALDH1A1 2951/4885MAPT 2228/4885HSP90AA1 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.