Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274224 | 0.86 | SMO (0.53) | SMONR3C1 | |
| SCHEMBL16300044 | 0.81 | SMO (0.55) | SMONR3C1 | |
| SCHEMBL27704310 | 0.80 | SMO (0.57) | SMONR3C1 | |
| SCHEMBL17892124 | 0.79 | SMO (0.52) | SMONR3C1 | |
| SCHEMBL4283364 | 0.77 | SMO (0.58) | SMONR3C1 | |
| SCHEMBL27704313 | 0.77 | SMO (0.49) | SMONR3C1 | |
| SCHEMBL4286821 | 0.76 | SMO (0.53) | SMONR3C1 | |
| SCHEMBL17892204 | 0.76 | SMO (0.50) | SMONR3C1 | |
| SCHEMBL22185372 | 0.76 | NR3C1 (0.52) | SMONR3C1 | |
| SCHEMBL4277837 | 0.75 | SMO (0.53) | SMONR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893588-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006135826-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-21 | — | — | WO | disclosed |