SCHEMBL476073

SCHEMBL476073

[CH2]C(=O)O[Si](C)(C)Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
KMT2A Q03164 2/20 0.38
CES1 P23141 2/20 0.38
MEN1 O00255 1/20 0.38
CES2 O00748 1/20 0.38
AKR1B1 P15121 1/20 0.38
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476074 0.83 ALDH1A1 (0.50) ALDH1A1NPC1RAB9ACA12CA9
SCHEMBL27952938 0.82 ALDH1A1 (0.42) ALDH1A1NPC1RAB9ACA12CA9
SCHEMBL475978 0.82 ALDH1A1 (0.43) ALDH1A1NPC1RAB9ACA12CA9
SCHEMBL476081 0.81 PLA2G10 (0.41) ALDH1A1KMT2ACES1CES2AKR1B1
SCHEMBL28365519 0.80 HCAR2 (0.46) ALDH1A1NPC1RAB9ACA12CA9
SCHEMBL475994 0.80 HDAC3 (0.44) ALDH1A1NPC1RAB9AKMT2ACES1
SCHEMBL1052706 0.77 CES1 (0.44) ALDH1A1KMT2ACES1MEN1
SCHEMBL5388447 0.73 TSHR (0.42) ALDH1A1TSHRLMNAHPGD
SCHEMBL3781076 0.73 CYP2C9 (0.40) ALDH1A1TSHRHPGD
SCHEMBL27730660 0.72 ALDH1A1 (0.50) ALDH1A1CES1CES2AKR1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2173780-B1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN AS (NO) 2012-05-23 EP disclosed
EP-2294148-B1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN AS (NO) 2012-02-01 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-20110123478-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2011-05-26 US disclosed
EP-2294148-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER Jotun A/S (NO) 2011-03-16 EP disclosed
EP-2173780-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER Jotun A/S (NO) 2010-04-14 EP disclosed
WO-2009149919-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2009-12-17 WO disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed