Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.41 |
| ▸ | CRAT | P43155 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570577 | 0.96 | PLA2G2C (0.41) | PLA2G2CCRATCA12CA1CA2 | |
| SCHEMBL4760783 | 0.80 | PLA2G2C (0.42) | PLA2G2CCRATCA12CA1CA2 | |
| SCHEMBL6570583 | 0.80 | PLA2G2C (0.42) | PLA2G2CCRATCA12CA1CA2 | |
| SCHEMBL6570305 | 0.78 | MTNR1A (0.34) | ACACBENPEP | |
| SCHEMBL8367402 | 0.74 | TAS1R3 (0.46) | PLA2G2CCRATCA12CA1CA2 | |
| SCHEMBL6569599 | 0.74 | MTNR1A (0.34) | ACACBENPEP | |
| SCHEMBL422585 | 0.73 | — | — | |
| SCHEMBL14007401 | 0.72 | PLA2G2C (0.40) | PLA2G2CCRATCA12CA1CA2 | |
| SCHEMBL4578510 | 0.72 | — | — | |
| SCHEMBL13715798 | 0.71 | PLA2G2C (0.59) | PLA2G2CCA1CA2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4156795-B2 | — | — | 2008-09-24 | — | — | JP | claimed |
| JP-2002501040-A | — | — | 2002-01-15 | — | — | JP | claimed |
| EP-1051393-A1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | LIPHA (FR) | 2000-11-15 | — | — | EP | claimed |
| WO-1999037606-A1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | LIPHA (FR) | 1999-07-29 | — | — | WO | claimed |