SCHEMBL4760959

SCHEMBL4760959

CCC(N)(S)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6159037 1.00
SCHEMBL11090141 0.97
SCHEMBL5689354 0.79
SCHEMBL2235565 0.79
SCHEMBL15421837 0.75 FDPS (0.43)
SCHEMBL5696081 0.74 ALDH1A1 (0.32)
SCHEMBL5696065 0.72 SMPD1 (0.47)
SCHEMBL9733997 0.72 SMPD1 (0.47)
SCHEMBL5696055 0.72 GRM2 (0.43)
SCHEMBL6882712 0.71 MEN1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4452781-A Method of treating bacterial viral or parasitic diseases PETROVICH VOJISLAV 1984-06-05 US claimed
JP-6199781-A None JP disclosed
WO-2022222907-A1 THIOLATED POLYSACCHARIDE DERIVATIVE HYDROGEL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 中国海洋大学 2022-10-27 WO disclosed
US-10308597-B2 Inhibitors of creatine transport and uses thereof RGENIX, INC. (US) 2019-06-04 US disclosed
US-20170050924-A1 INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF INSPIRNA, INC. 2017-02-23 US disclosed
EP-1874800-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS Karyon-CTT Ltd (FI) 2008-01-09 EP disclosed
WO-2006114478-A1 DIAGNOSTIC AND THERAPEUTIC AGENTS KARYON-CTT LTD (FI) 2006-11-02 WO disclosed
EP-0900210-B1 ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES NOVARTIS AG (CH) 2005-02-09 EP disclosed
US-6300519-B1 REACTING HYDRAZINE DERIVATIVE WITH EPOXIDE COMPOUND NOVARTIS FINANCE CORPORATION 2001-10-09 US disclosed
US-6166004-A Combinations of HIV protease inhibitors with reverse transcriptase inhibitors NOVARTIS FINANCE CORPORATION (US) 2000-12-26 US disclosed
US-6110946-A AN ENZYME INHIBITORS OF RETROVIRAL ASPARTATE PROTEASE FOR THE TREATMENT OF AIDS NOVARTIS FINANCE CORPORATION (US) 2000-08-29 US disclosed
EP-0900210-A1 ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES Novartis AG (CH) 1999-03-10 EP disclosed
US-5849911-A Antivirally active heterocyclic azahexane derivatives NOVARTIS FINANCE CORPORATION (US) 1998-12-15 US disclosed
WO-1997040029-A1 ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES NOVARTIS AG (CH) 1997-10-30 WO disclosed
JP-H06199781-A PRODUCTION OF OPTICALLY ACTIVE 4-MERCAPTO-2-PYRROLIDONE DERIVATIVE AND ITS SYNTHETIC INTERMEDIATE TANABE SEIYAKU CO LTD 1994-07-19 JP disclosed
US-4452781-A Method of treating bacterial viral or parasitic diseases PETROVICH VOJISLAV 1984-06-05 US disclosed
US-4452781-A Method of treating bacterial viral or parasitic diseases PETROVICH VOJISLAV 1984-06-05 US disclosed
US-4204064-A FOR TREATMENT OF SKIN OR SCALP L'OREAL (FR) 1980-05-20 US disclosed
US-4085217-A DERIVATIVES OF CYSTEINE OR CYSTEAMINE L'OREAL (FR) 1978-04-18 US disclosed
US-3976781-A SULFUR CONTAINING AMINES L'OREAL (FR) 1976-08-24 US disclosed