Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Cellobiose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.54 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.54 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 8/20 | 0.49 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | AMY2A | P04746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | IGF2R | P11717 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maltose SCHEMBL9704098 | 0.98 | LGALS8 (0.53) | LGALS8LGALS3LGALS4MAPTBLM | |
| Sulfuric Acid SCHEMBL8756855 | 0.92 | MAPT (0.55) | LGALS8LGALS3LGALS4MAPTBLM | |
| Cellobiose SCHEMBL23708014 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| Cellobiose SCHEMBL21114355 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| Maltotriose SCHEMBL20553487 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| Cellobiose SCHEMBL23752618 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| Maltotriose SCHEMBL23467170 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| Maltotriose SCHEMBL24202675 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| SCHEMBL21752778 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 | |
| Cellobiose SCHEMBL24662526 | 0.92 | LGALS8 (0.61) | LGALS8LGALS3LGALS4AMY2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008229435-A | SUGAR CHAIN POLYMER MOBILIZED FILTER WHICH REMOVES TOXIN AND VIRUS | UNIV OF TOKYO | 2008-10-02 | — | — | JP | disclosed |