SCHEMBL476128

SCHEMBL476128

C[SiH](C)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
CALM1 P0DP23 1/20 0.45
TAAR1 Q96RJ0 4/20 0.44
SLC6A2 P23975 2/20 0.44
TSHR P16473 4/20 0.42
ALDH1A1 P00352 4/20 0.42
IDO1 P14902 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TRPA1 O75762 1/20 0.41
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28075257 0.97 TP53 (0.46) TP53CALM1TAAR1SLC6A2TSHR
SCHEMBL7188839 0.84 ALDH1A1 (0.31) ALDH1A1IDO1
SCHEMBL23532340 0.82 TP53 (0.34) TP53CALM1TAAR1SLC6A2TSHR
SCHEMBL6960735 0.82 TP53 (0.48) TP53CALM1TAAR1SLC6A2TSHR
SCHEMBL14366695 0.80 MEN1 (0.36) TP53TAAR1SLC6A2ALDH1A1IDO1
SCHEMBL15302135 0.78 TSHR (0.43) TP53CALM1TAAR1SLC6A2TSHR
SCHEMBL3192456 0.78 TP53 (0.43) TP53CALM1TAAR1SLC6A2TSHR
SCHEMBL29875499 0.78 TP53 (0.43) TP53CALM1TAAR1SLC6A2TSHR
SCHEMBL15302282 0.78 TSHR (0.43) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL15302534 0.78 TP53 (0.43) TP53CALM1TAAR1SLC6A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720033-A1 PROCESS FOR TRAPPING THIOCARBONYL FLUORIDE Centre National de la Recherche Scientifique (FR) 2026-04-08 EP claimed
EP-4471011-B1 PROCESS FOR THE SELECTIVE CLEAVAGE OF C-SCF3 BONDS AND ANALOGUES CENTRE NAT RECH SCIENT (FR) 2026-01-14 EP claimed
CN-119392404-A Polyether-ether-ketone polishing brush wire material and preparation method thereof 广州傲群刷业科技有限公司 2025-02-07 CN claimed
WO-2024246226-A1 PROCESS FOR THE SELECTIVE CLEAVAGE OF C-SCF3 BONDS AND ANALOGUES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-12-05 WO claimed
WO-2024246241-A1 PROCESS FOR TRAPPING THIOCARBONYL FLUORIDE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-12-05 WO claimed
EP-4471011-A1 PROCESS FOR THE SELECTIVE CLEAVAGE OF C-SCF3 BONDS AND ANALOGUES Centre National de la Recherche Scientifique (FR) 2024-12-04 EP claimed
EP-4471009-A1 PROCESS FOR TRAPPING THIOCARBONYL FLUORIDE Centre National de la Recherche Scientifique (FR) 2024-12-04 EP claimed
CN-118638144-A Synthesis method of heteroaryl silane 南阳师范学院 2024-09-13 CN claimed
CN-117865999-A Preparation method of silicon-based benzazepine-ketone compound 烟台大学 2024-04-12 CN claimed
WO-2023161688-A1 SILA-ANALOGUES OF VITAMIN D COMPOUNDS, METHOD OF PRODUCING SAID COMPOUNDS AND USES THEREOF REQUIMTE - REDE DE QUÍMICA E TECNOLOGIA (PT) 2023-08-31 WO claimed
EP-1124865-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE OLEFIN Bayer Inc. (CA) 2001-08-22 EP claimed
EP-0793497-A4 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF SLOAN KETTERING INST CANCER (US) 1998-01-28 EP claimed
EP-0793497-A1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF Sloan-Kettering Institute For Cancer Research (US) 1997-09-10 EP claimed
WO-1996016655-A1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-06-06 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
EP-0291787-B1 Novel substituted silyl alkylene amines MERRELL DOW PHARMA (US) 1994-03-16 EP claimed
US-5164525-A SYNTHETIC PROCESS FOR FK-506 TYPE MACROLIDE INTERMEDIATES MERCK & CO., INC. (US) 1992-11-17 US claimed
EP-0405994-A2 Synthetic process for FK-506 type macrolide intermediates MERCK & CO. INC. (US) 1991-01-02 EP claimed
EP-0291787-A1 Novel substituted silyl alkylene amines MERRELL DOW PHARMACEUTICALS INC. (US) 1988-11-23 EP claimed