SCHEMBL6960735

SCHEMBL6960735

C[SiH](Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
CALM1 P0DP23 1/20 0.45
TSHR P16473 4/20 0.42
ALDH1A1 P00352 4/20 0.42
IDO1 P14902 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TRPA1 O75762 1/20 0.41
LMNA P02545 1/20 0.41
CYP2D6 P10635 1/20 0.41
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476128 0.82 TP53 (0.48) TP53CALM1TSHRALDH1A1IDO1
Fluoride SCHEMBL28075257 0.80 TP53 (0.46) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL15302282 0.78 TSHR (0.43) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL15302534 0.78 TP53 (0.43) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL3192456 0.78 TP53 (0.43) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL15302135 0.78 TSHR (0.43) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL29875499 0.78 TP53 (0.43) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL703318 0.77 TP53 (0.48) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL9239449 0.76 TP53 (0.42) TP53CALM1TSHRALDH1A1IDO1
SCHEMBL41196 0.75 CALM1 (0.50) TP53CALM1TSHRALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0793497-B1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF SLOAN KETTERING INST CANCER (US) 2003-02-12 EP claimed
EP-0793497-A4 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF SLOAN KETTERING INST CANCER (US) 1998-01-28 EP claimed
EP-0793497-A1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF Sloan-Kettering Institute For Cancer Research (US) 1997-09-10 EP claimed
WO-1996016655-A1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-06-06 WO claimed
EP-3239111-B1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM CORP (JP) 2021-02-17 EP disclosed
EP-3239111-A1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM Corporation (JP) 2017-11-01 EP disclosed
US-9359505-B2 Gas barrier film, process for production of gas barrier film, and electronic device KONICA MINOLTA HOLDINGS, INC. (JP) 2016-06-07 US disclosed
US-9268451-B2 Transfer film, manufacturing method of capacitive input device, capacitive input device, and image display device including the same FUJIFILM CORPORATION (JP) 2016-02-23 US disclosed
US-20150092123-A1 TRANSFER FILM, MANUFACTURING METHOD OF CAPACITIVE INPUT DEVICE, CAPACITIVE INPUT DEVICE, AND IMAGE DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-04-02 US disclosed
EP-2599621-A1 GAS BARRIER FILM, PROCESS FOR PRODUCTION OF GAS BARRIER FILM, AND ELECTRONIC DEVICE Konica Minolta Holdings, Inc. (JP) 2013-06-05 EP disclosed
US-20130115423-A1 GAS BARRIER FILM, PROCESS FOR PRODUCTION OF GAS BARRIER FILM, AND ELECTRONIC DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-05-09 US disclosed
EP-0711762-B1 PROCESS FOR PRODUCING TETRAZOLE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2003-08-06 EP disclosed
US-5707547-A CONTAINING FLUORINATED BENZENE OR NAPHTHALENE RINGS AND/OR NITROGEN CONTAINING HETEROCYCLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-01-13 US disclosed
EP-0793497-A1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF Sloan-Kettering Institute For Cancer Research (US) 1997-09-10 EP disclosed
WO-1996016655-A1 NOVEL ENEDIYNE QUINONE IMINES AND METHODS OF PREPARATION AND USE THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-06-06 WO disclosed
EP-0711762-A1 PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-05-15 EP disclosed
EP-0643119-A1 Trans-olefin compounds, method for production thereof, liquid crystal composition containing the same as active ingredient, and liquid crystal element using said composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-15 EP disclosed
EP-0191260-B1 PENTACOORDINATED SILICON COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PREPARING ORGANOSILANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-05-31 EP disclosed
US-4617413-A Pentacoordinate silicon complexes, the process for their preparation and their application to the preparation of organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1986-10-14 US disclosed
EP-0191260-A1 Pentacoordinated silicon complexes, process for their preparation and their use in preparing organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-08-20 EP disclosed