Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284059 | 0.93 | MAPK14 (0.45) | BRAFMAPK14CNR2CNR1MAPT | |
| SCHEMBL476143 | 0.85 | CNR2 (0.51) | BRAFMAPK14CNR2CNR1MAPT | |
| SCHEMBL283286 | 0.84 | CNR1 (0.56) | MAPK14CNR2CNR1 | |
| SCHEMBL283743 | 0.80 | CNR2 (0.43) | MAPK14CNR2CNR1MAPTLMNA | |
| SCHEMBL5201677 | 0.79 | MAPK14 (0.43) | BRAFMAPK14CNR2MAPTLMNA | |
| SCHEMBL4139014 | 0.77 | CNR2 (0.56) | MAPK14CNR2MAPTLMNAMAPK13 | |
| SCHEMBL283058 | 0.75 | MAPK14 (0.53) | MAPK14CNR2CNR1MAPK13 | |
| SCHEMBL283651 | 0.73 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL283980 | 0.73 | MAPK14 (0.49) | MAPK14MAPK13 | |
| SCHEMBL16279349 | 0.73 | MAPK14 (0.43) | BRAFMAPK14CNR2CNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411370-B1 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBVIE INC (US) | 2015-04-22 | — | — | EP | disclosed |
| EP-2411370-A1 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111573-A1 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-09-30 | — | — | WO | disclosed |