Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283058 | 0.89 | MAPK14 (0.53) | MAPK14MAPK13CNR2 | |
| SCHEMBL284059 | 0.85 | MAPK14 (0.45) | MAPK14MAPTLMNAMAPK13MAPK11 | |
| SCHEMBL283980 | 0.84 | MAPK14 (0.49) | MAPK14MAPK13 | |
| SCHEMBL283651 | 0.84 | MAPK14 (0.49) | MAPK14MAPK13MAPK11MAPK12 | |
| SCHEMBL476143 | 0.82 | CNR2 (0.51) | MAPK14MAPTLMNACNR2BRAF | |
| SCHEMBL283286 | 0.81 | CNR1 (0.56) | MAPK14CNR2 | |
| SCHEMBL288767 | 0.81 | MAPK14 (0.47) | MAPK14MAPK13CNR2 | |
| SCHEMBL283743 | 0.80 | CNR2 (0.43) | MAPK14MAPTLMNACNR2MAPK1 | |
| SCHEMBL476129 | 0.79 | BRAF (0.42) | MAPK14MAPTLMNAMAPK13MAPK11 | |
| SCHEMBL4139014 | 0.79 | CNR2 (0.56) | MAPK14MAPTLMNAMAPK13MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820504-A1 | IMINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-08-22 | — | — | EP | disclosed |