SCHEMBL4761561

SCHEMBL4761561

Nc1ccc(Cc2ccc(N)cc2C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
CYP3A4 P08684 3/20 0.52
KDM4E B2RXH2 3/20 0.52
THRB P10828 2/20 0.52
RECQL P46063 2/20 0.52
USP2 O75604 1/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
APEX1 P27695 1/20 0.52
BLM P54132 1/20 0.52
MCL1 Q07820 1/20 0.52
TNF P01375 1/20 0.52
HSPD1 P10809 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714231 0.89 ALDH1A1 (0.59) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL16852602 0.86 ALDH1A1 (0.51) ALDH1A1TDP1CYP3A4MCL1TSHR
SCHEMBL15796669 0.82 TSHR (0.72) ALDH1A1TDP1CYP3A4CYP2C9ALOX15
SCHEMBL8477515 0.79 KDM4E (0.57) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL34474732 0.79 KDM4E (0.57) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL8477518 0.79 KDM4E (0.57) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL9469346 0.79 ALDH1A1 (0.57) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL27607764 0.78 KDM4E (0.55) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL2386426 0.78 KDM4E (0.55) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL27569546 0.78 KDM4E (0.55) ALDH1A1TDP1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1182367-A None JP disclosed
WO-2021029243-A1 COLORED RESIN COMPOSITION, CURED PRODUCT AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
WO-2021028960-A1 COLORED RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE 太陽ホールディングス株式会社 2021-02-18 WO disclosed
JP-2008248067-A POLYIMIDE FILM AND FLEXIBLE CIRCUIT BOARD DU PONT TORAY CO LTD 2008-10-16 JP disclosed
JP-2007039527-A POLYIMIDE FILM AND FLEXIBLE CIRCUIT BOARD DU PONT TORAY CO LTD 2007-02-15 JP disclosed
JP-2007039528-A POLYIMIDE FILM, ITS MANUFACTURING METHOD AND FLEXIBLE CIRCUIT BOARD DU PONT TORAY CO LTD 2007-02-15 JP disclosed
JP-2006176581-A POLYAMIC ACID, POLYIMIDE FILM MADE THEREFROM, ITS PRODUCTION METHOD AND FLEXIBLE CIRCUIT BOARD DU PONT TORAY CO LTD 2006-07-06 JP disclosed
JP-H01182367-A ANTHRONE DERIVATIVE AND HEAT-SENSITIVE RECORDING MATERIAL USING SAME SHOWA DENKO KK 1989-07-20 JP disclosed