Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761767 | 0.90 | TBXA2R (0.50) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL4761012 | 0.90 | MAPT (0.49) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL4761006 | 0.80 | MAPT (0.52) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL27675773 | 0.79 | CYP1A2 (0.53) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL21295362 | 0.78 | TBXA2R (0.47) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL14864858 | 0.77 | MAPT (0.58) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL10424523 | 0.76 | MAPT (0.56) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL21654259 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2ALMNACYP1A2SMN1; SMN2 | |
| SCHEMBL5553432 | 0.75 | MAPT (0.55) | TBXA2RMAPTMEN1KMT2ALMNA | |
| SCHEMBL1553699 | 0.74 | MAPT (0.57) | TBXA2RMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957495-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007064045-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |