Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119963 | 0.87 | POLB (0.40) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL21702346 | 0.78 | KMT2A (0.35) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL3620210 | 0.75 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL9644333 | 0.73 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL8524708 | 0.73 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1KMT2ATSHRHPGD | |
| SCHEMBL8485222 | 0.72 | CDC7 (0.46) | L3MBTL1ALDH1A1KMT2ATSHRHPGD | |
| SCHEMBL2444646 | 0.69 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL20439944 | 0.67 | TSHR (0.43) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL1724016 | 0.66 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1POLBKMT2ATSHR | |
| SCHEMBL3119779 | 0.66 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991545-A2 | ANTIBACTERIAL PYRROLOPYRIDINES, PYRROLOPYRIMIDINES, AND PYRROLOAZEPINES | AstraZeneca AB (SE) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007071965-A2 | ANTIBACTERIAL PYRROLOPYRIDINES, PYRROLOPYRIMIDINES, AND PYRROLOAZEPINES | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |