Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275271 | 0.65 | CYP2B6 (0.46) | CYP1A2CYP1B1CA1CA9CYP1A1 | |
| SCHEMBL4510020 | 0.65 | CYP1A2 (0.40) | CYP1A2CYP1B1CA1CA9CYP1A1 | |
| SCHEMBL9626791 | 0.65 | CYP1A2 (0.46) | CYP1A2CYP1B1CA1CA9CYP1A1 | |
| SCHEMBL4712134 | 0.65 | CYP1A2 (0.40) | CYP1A2CYP1B1CA1CA9CYP1A1 | |
| SCHEMBL23753756 | 0.64 | PARP1 (0.31) | — | |
| SCHEMBL29207958 | 0.63 | CYP1A2 (0.58) | CYP1A2CYP1B1CA9CYP1A1CYP2B6 | |
| SCHEMBL13113614 | 0.63 | CYP2B6 (0.43) | CYP1A2CYP1B1CA1CA9CYP1A1 | |
| SCHEMBL30291346 | 0.63 | CYP2B6 (0.43) | CYP1A2CYP1B1CA1CA9CYP1A1 | |
| SCHEMBL1477703 | 0.62 | MTNR1A (0.41) | CYP1A2CYP1B1CYP1A1CYP2B6MTNR1A | |
| SCHEMBL2009226 | 0.62 | CYP2B6 (0.43) | CYP1A2CYP1B1CA1CA9CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008208098-A | 2H-PYRANO[3,2-c]PYRIDIN-5(6H)-ONE DERIVATIVE | HIROSHIMA UNIV | 2008-09-11 | — | — | JP | disclosed |