⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16908691 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL16908690 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL1376046 | 0.77 | ACLY (0.35) | — | |
| SCHEMBL7171837 | 0.75 | ALDH1A1 (0.47) | — | |
| SCHEMBL528085 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL11812638 | 0.75 | TSHR (0.46) | — | |
| SCHEMBL293485 | 0.75 | — | — | |
| SCHEMBL30513348 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL8882940 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL3256852 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773856-B1 | PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | PHARMASSET INC (US) | 2012-02-01 | — | — | EP | claimed |
| US-7601820-B2 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET, INC. (US) | 2009-10-13 | — | — | US | claimed |
| EP-1773856-A2 | PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | Pharmasset, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| US-20060199783-A1 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSETT, INC. (US) | 2006-09-07 | — | — | US | claimed |
| WO-2006012440-A2 | PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | PHARMASSET, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| EP-4347547-A1 | PREPARATION OF AN INTERMEDIATE IN THE SYNTHESIS OF 2-CYCLODODECYL-1-PROPANOL | Miltitz Aromatics GmbH (DE) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022253626-A1 | PREPARATION OF AN INTERMEDIATE IN THE SYNTHESIS OF 2-CYCLODODECYL-1-PROPANOL | MILTITZ AROMATICS GMBH (DE) | 2022-12-08 | — | — | WO | disclosed |
| EP-2348029-A1 | Preparation of alkyl-substituted 2-deoxy-2-fluoro-d-ribofuranosyl pyrimidines and purines and their derivatives | Pharmasset, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| US-7678869-B2 | Atom or group transfer radical polymerization | CARNEGIE MELLON UNIVERSITY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20060258826-A1 | Atom or group transfer radical polymerization | CARNEGIE MELLON UNIVERSITY | 2006-11-16 | — | — | US | disclosed |
| EP-0966489-B1 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | UNIV CARNEGIE MELLON (US) | 2006-11-15 | — | — | EP | disclosed |
| US-7125938-B2 | Atom or group transfer radical polymerization | CARNEGIE MELLON UNIVERSITY (US) | 2006-10-24 | — | — | US | disclosed |
| EP-0966489-A4 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | UNIV CARNEGIE MELLON (US) | 2002-03-06 | — | — | EP | disclosed |
| US-6117822-A | AS HERBICIDES AND PLANT DESICCANTS AND/OR DEFOLIANTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-12 | — | — | US | disclosed |
| EP-0966489-A1 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | CARNEGIE MELLON UNIVERSITY (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998040415-A1 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | CARNEGIE MELLON UNIVERSITY (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5807807-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5707937-A | AGRICULTURAL HERBICIDES, DESICCANTS, DEFOLIANTS, HARVESTING AIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0601573-A1 | Alpha-phosphonocarboxylate squalene synthetase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5312814-A | Antilipemic agents or anticholesterol agents | BRISTOL-MYERS SQUIBB CO. (US) | 1994-05-17 | — | — | US | disclosed |