Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 10/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.79 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.79 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.79 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR2C | P28335 | 6/20 | 0.59 |
| ▸ | HTR2B | P41595 | 6/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30249887 | 1.00 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| Hydrochloric Acid SCHEMBL158709 | 0.98 | PNMT (0.96) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL1772370 | 0.89 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| Hydrochloric Acid SCHEMBL11211829 | 0.87 | PNMT (1.00) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL11327857 | 0.82 | PNMT (0.70) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL11322190 | 0.82 | PNMT (0.70) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL11334166 | 0.82 | PNMT (0.70) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL11340596 | 0.82 | PNMT (0.70) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL11336373 | 0.82 | PNMT (0.70) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL11325747 | 0.82 | PNMT (0.70) | PNMTADRA2AADRA2BADRA2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143322-A1 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) | 2010-06-10 | — | — | US | claimed |
| EP-1917006-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT Patent & Licence Trading Ltd. (GB) | 2008-05-07 | — | — | EP | claimed |
| WO-2006136454-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD. (GB) | 2006-12-28 | — | — | WO | claimed |
| EP-0002624-B1 | 2-BENZAZEPINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-14 | — | — | EP | claimed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024187194-A2 | PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS | TRUSTEES OF TUFTS COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| EP-1049807-A4 | MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS | LUMINEX CORP (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6268222-B1 | Microparticles attached to nanoparticles labeled with flourescent dye | LUMINEX CORPORATION | 2001-07-31 | — | — | US | disclosed |
| WO-2001013120-A1 | MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS AND METHODS OF USING SAME | LUMINEX CORPORATION (US) | 2001-02-22 | — | — | WO | disclosed |
| EP-1049807-A1 | MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS | Luminex Corporation (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037814-A9 | MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS | LUMINEX CORP (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999037814-A1 | MICROPARTICLES WITH MULTIPLE FLUORESCENT SIGNALS | LUMINEX CORPORATION (US) | 1999-07-29 | — | — | WO | disclosed |
| EP-0002624-B1 | 2-BENZAZEPINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | disclosed |