Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766397 | 0.82 | CSNK1A1 (0.51) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL4765894 | 0.80 | CSNK1A1 (0.50) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL4770518 | 0.78 | CSNK1A1 (0.47) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL4768126 | 0.77 | CNR1 (0.46) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL4768640 | 0.75 | POLB (0.49) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL4773544 | 0.75 | CSNK1A1 (0.55) | CSNK1A1CLK4ALDH1A1PIN1PGK1 | |
| SCHEMBL4772159 | 0.75 | CSNK1A1 (0.47) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL27502303 | 0.75 | CSNK1A1 (0.51) | CSNK1A1CLK4ALDH1A1PIN1HPGD | |
| SCHEMBL4765379 | 0.74 | CSNK1A1 (0.44) | CSNK1A1CLK4L3MBTL1ALDH1A1PIN1 | |
| SCHEMBL4579364 | 0.74 | SMN1; SMN2 (0.45) | CSNK1A1CLK4ALDH1A1PIN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303496-B9 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1303496-B1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-09-12 | — | — | EP | disclosed |