Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041867 | 0.89 | TTR (0.45) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL11047153 | 0.87 | AURKA (0.45) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL28118203 | 0.83 | AURKA (0.44) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL28065908 | 0.83 | AURKA (0.50) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL27999216 | 0.80 | TTR (0.46) | TTRAURKAAURKBHSD17B10ALDH1A1 | |
| SCHEMBL2161129 | 0.78 | AURKA (0.49) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL179823 | 0.77 | TTR (0.58) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL29360969 | 0.77 | TTR (0.58) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL11433276 | 0.77 | AURKA (0.47) | TTRAURKAAURKBCYP1A2HSD17B10 | |
| SCHEMBL30819408 | 0.77 | SUMO2 (0.53) | TTRAURKAAURKBCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883821-A1 | AUTOMATED GLYCOFINGERPRINTING STRATEGY | Dwek, Raymond A. (GB) | 2008-02-06 | — | — | EP | claimed |
| WO-2006114663-A1 | AUTOMATED GLYCOFINGERPRINTING STRATEGY | DWEK RAYMOND A (GB) | 2006-11-02 | — | — | WO | claimed |
| US-6897196-B1 | pH sensitive lipids based on ortho ester linkers, composition and method | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-24 | — | — | US | disclosed |
| US-6746868-B1 | PEPTIDE NUCLEIC ACIDS LINKED TO PEPTIDES WHICH HYBRIDIZE TO DNA AND CAN BE USED TO MONITOR THE INTRACELLULAR LOCATION OF EXOGENOUS TRANSFECTED DNA AND TO PROMOTE VARIOUS INTRACELLULAR PROCESSES | ISIS PHARMACEUTICALS, INC. | 2004-06-08 | — | — | US | disclosed |
| US-6165720-A | Chemical modification of DNA using peptide nucleic acid conjugates | GENE THERAPY SYSTEMS (US) | 2000-12-26 | — | — | US | disclosed |